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Nicholas P Bleeker Selected Research

ethyl 2- amino- 6- (3,5- dimethoxyphenyl)- 4- (2- ethoxy- 2- oxoethyl)- 4H- chromene- 3- carboxylate

11/2013A novel SERCA inhibitor demonstrates synergy with classic SERCA inhibitors and targets multidrug-resistant AML.
6/2012Structure-activity relationship (SAR) study of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and the potential of the lead against multidrug resistance in cancer treatment.
8/2011Structure-activity relationship and molecular mechanisms of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and its analogues.

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Nicholas P Bleeker Research Topics

Disease

4Neoplasms (Cancer)
11/2013 - 08/2011
1Leukemia
11/2013

Drug/Important Bio-Agent (IBA)

3ethyl 2- amino- 6- (3,5- dimethoxyphenyl)- 4- (2- ethoxy- 2- oxoethyl)- 4H- chromene- 3- carboxylateIBA
11/2013 - 08/2011
2Pharmaceutical PreparationsIBA
11/2013 - 08/2011
1Adenosine Triphosphatases (ATPase)IBA
11/2013
1AlkaloidsIBA
10/2012
1Antineoplastic Agents (Antineoplastics)IBA
06/2012
1Mitoxantrone (Novantrone)FDA LinkGeneric
08/2011

Therapy/Procedure

2Therapeutics
06/2012 - 08/2011